Cosmo Bio Ltd
Established in 1983, Cosmo Bio is a Japanese company that distributes its own research reagents, and the products of trusted Japanese partners, to support life science research worldwide. With a portfolio comprising over 5000 export quality antibodies, proteins, ELISA kits, cell biology and molecular biology reagents, as well as general consumables, Cosmo Bio serves a wide range of customer requirements.
Cosmo Bio’s mouse IVF products are especially of interest to our customers. Using Cosmo Bio’s ultra-superovulation reagent, CARD HyperOva, in combination with CARD FERTIUP® preincubation medium, CARD medium, and CARD mHTF, all of which are recommended by the Centre of Animal Resources and Development (CARD), researchers can perform murine in vitro fertilisation to successfully achieve 2-cell to blastocyst stage embryos via a relatively straightforward protocol.
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Researchers also turn to us for Cosmo Bio’s transfection reagents. We notice a lot of attention focused on Cosmo Bio’s GenomONE-Neo™, a unique product for transfection of nucleic acids, proteins, and small molecules. This delivers extremely efficient gene expression by utilising the high membrane fusion potential of inactivated Sendai virus particle (hemagglutinating virus of Japan envelope, HVJ-E). Unlike conventional non-virus transfection tools, HVJ-E has the capacity to resist degradation by lysosomes. Cosmo Bio’s cell fusion reagent, GenomONE™-CF EX, is another of our more popular products.
Also based on HVJ-E, this can be used with both adherent and suspension cells to achieve fusion in just 30 minutes. In combination with hybridoma growth supplement, GenomONE™-CF EX demonstrates a 100% antibody-production positive rate as compared to just 9% with PEG1500 under identical conditions, making it a superior alternative to traditional PEG-based methods of cell fusion.