anti-p53 antibody [Pab1801]
Product Sizes
50 ug
ARG10519-50UG
100 ug
ARG10519-100UG
About this Product
- SKU:
- ARG10519
- Additional Names:
- TRP53; LFS1; Cellular tumor antigen p53; Phosphoprotein p53; Tumor suppressor p53; BCC7; Antigen NY-CO-13; P53
- Application:
- ChIP, ELISA, Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Radioimmunoassay, Western Blot
- Buffer:
- PBS and 0.02% Sodium azide.
- CE/IVD:
- RUO
- Clone:
- Pab 1801
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- p53 is a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
- Host:
- Mouse
- Isotype:
- IgG1
- Purification:
- Protein A Purified; Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:ARG10519.html
