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Antibodies

anti-FOX3 / NeuN antibody [1B7]

Product Sizes
50 ul
ARG52283-50UL
100 ul
ARG52283-100UL
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG52283
Additional Names:
RNA binding protein fox-1 homolog 3; NEUN; FOX-3; HRNBP3; Fox-1 homolog C; FOX3
Application:
IHC-Frozen, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Western Blot
Buffer:
PBS and 10 mM Sodium azide.
CE/IVD:
RUO
Clone:
1B7
Clonality:
Monoclonal
Extra Details:
FOX3, also known as NeuN and hexaribonucleotide binding protein 3, is a neuron-specific RNA binding nuclear protein involved in the regulation of pre-mRNA alternative splicing (Kim et al., 2009). FOX3 dependent alternative splicing of Numb has recently been shown to play an important role in the progression of neuronal differentiation during vertebrate development (Kim et al., 2013).
Host:
Mouse
Isotype:
IgG2a
Purification:
Affinity Purified
Reactivities:
Avian, Bovine, Canine, Feline, Goat, Human, Mouse, Porcine, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Monoclonal Antibody
Western Blot: Rat cortex lysate showing specific immunolabeling of the ~46/48k FOX3 protein stained with ARG52283 anti-FOX3 / NeuN antibody [1B7].
Immunofluorescence: Cultured Rat neurons stained with ARG52283 anti-FOX3 / NeuN antibody [1B7] showing strong nuclear and distal cytoplasmic staining of FOX3 in red and the complete absence of astrocyte staining, which are stained in green with ARG52313 anti-GFAP antibody.
Immunohistochemistry: Adult Rat hippocampus stained with anti-c-Fos antibody (red) and DNA (blue). ARG52283 anti-FOX3 / NeuN antibody [1B7] (green) reveals strong nuclear and distal cytoplasmic staining for hippocampal neurons and the complete absence of staining of nonneuronal cells.
Immunohistochemistry: Formalin-fixed and paraffin-embedded Rat brain stem neurons stained with ARG52283 anti-FOX3 / NeuN antibody [1B7] (green) and counter stained with anti-MAP2 antibody (red). The nuclei of cells are revealed with DAPI in blue.
Western blot: Rat brain, Rat brain (embryonic, E20) and Mouse brain lysates stained with ARG52283 anti-FOX3 / NeuN antibody [1B7] (green) at 1:1000 dilution.