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Antibodies

anti-CD206 / MMR antibody [15-2]

Product Sizes
100 ug
ARG55554-100UG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG55554
Additional Names:
CLEC13D; C-type lectin domain family 13 member D; Macrophage mannose receptor 1-like protein 1; C-type lectin domain family 13 member D-like; MMR; CLEC13DL; CD206; Macrophage mannose receptor 1; bA541I19.1; CD antigen CD206; MRC1L1
Application:
Cell-based/Functional Assay, Flow Cytometry, IHC-Frozen, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Mass Cytometry, Western Blot
Buffer:
PBS (pH 7.4) and 15 mM Sodium azide
CE/IVD:
RUO
Clone:
15-2
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. CD206 / MMR is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. [provided by RefSeq, Sep 2015]
Host:
Mouse
Isotype:
IgG1
Purity:
>95%
Purification:
Protein A Purified; Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Specificity:
This antibody recognizes an extracellular epitope of CD206 (macrophage mannose receptor, MMR), a 162-175 kDa type I transmembrane protein expressed mainly on macrophages, dendritic cells and hepatic or lymphatic endothelial cells, but not on monocytes.
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Monoclonal Antibody
Flow Cytometry: Stimulated (GM-CSF + IL-4) human peripheral blood mononuclear cells stained with ARG55554 anti-CD206 / MMR antibody [15-2] at 9 ug/ml dilution, followed by PE-conjugated Goat anti-Mouse antibody.
Flow Cytometry: Separation of human CD206 positive dendritic cells differentiated upon monocyte stimulation (GM-CSF + IL-4) (red-filled) from non-stimulated lymphocytes (black-dashed). Human stimulated (GM-CSF + IL-4) peripheral blood mononuclear cells stained with ARG55554 anti-CD206 / MMR antibody [15-2] at 9 ug/ml dilution, followed by PE-conjugated Goat anti-Mouse antibody.
Immunohistochemistry: Frozen section of Human tonsil tissue stained with ARG55554 anti-CD206 / MMR antibody [15-2] at 1:25 dilution. The antibody stains endothelia of lymph vessels strongly.