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Antibodies

anti-SAPK / JNK phospho (Thr183) antibody

Product Sizes
100 ug
ARG66184-100UG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG66184
Additional Names:
MAP kinase 8; PRKM8; JNK1; c-Jun N-terminal kinase 1; Stress-activated protein kinase JNK1; MAPK 8; SAPK1c; JNK21B1/2; JNK-46; Mitogen-activated protein kinase 8; EC 2.7.11.24; JNK1A2; JNK; Stress-activated protein kinase 1c; SAPK1
Application:
IHC-Paraffin, Western Blot
Buffer:
PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
CE/IVD:
RUO
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jun 2013]
Host:
Rabbit
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Specificity:
The antibody detects endogenous SAPK / JNK protein only when phosphorylated at Thr183.
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Polyclonal Antibody
Immunohistochemistry: Paraffin-embedded Rat kidney tissue stained with ARG66184 anti-SAPK / JNK phospho (Thr183) antibody at 1:200 dilution (4°C, overnight). Antigen Retrieval: Boil tissue section in Sodium citrate buffer (pH 6.0) for 20 min.
Immunohistochemistry: Paraffin-embedded Rat testis tissue stained with ARG66184 anti-SAPK / JNK phospho (Thr183) antibody at 1:200 dilution (4°C, overnight). Antigen Retrieval: Boil tissue section in Sodium citrate buffer (pH 6.0) for 20 min.
Immunohistochemistry: Paraffin-embedded Rat spinal-cord tissue stained with ARG66184 anti-SAPK / JNK phospho (Thr183) antibody at 1:200 dilution (4°C, overnight). Antigen Retrieval: Boil tissue section in Sodium citrate buffer (pH 6.0) for 20 min.
Immunohistochemistry: Paraffin-embedded Mouse testis tissue stained with ARG66184 anti-SAPK / JNK phospho (Thr183) antibody at 1:200 dilution (4°C, overnight). Antigen Retrieval: Boil tissue section in Sodium citrate buffer (pH 6.0) for 20 min.
Immunohistochemistry: Paraffin-embedded Human colon tissue stained with ARG66184 anti-SAPK / JNK phospho (Thr183) antibody at 1:200 dilution (4°C, overnight). Antigen Retrieval: Boil tissue section in Sodium citrate buffer (pH 6.0) for 20 min.