anti-ASC / TMS1 antibody
About this Product
- SKU:
- ARG66211
- Additional Names:
- Apoptosis-associated speck-like protein containing a CARD; TMS; PYD and CARD domain-containing protein; hASC; ASC; TMS-1; TMS1; Caspase recruitment domain-containing protein 5; Target of methylation-induced silencing 1; CARD5
- Application:
- Western Blot
- Buffer:
- PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol.
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 1.28 mg/ml
- Extra Details:
- ASC / TMS1 is an adaptor protein. It is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Host:
- Rabbit
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ARG66211.html
