anti-Vinculin antibody
About this Product
- SKU:
- ARG66958
- Additional Names:
- HEL114; Metavinculin; CMH15; Vinculin; CMD1W; MV; MVCL
- Application:
- IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- 100 mM Tris Glycine (pH 7.0), 0.025% ProClin 300 and 20% Glycerol.
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Extra Details:
- Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
- Host:
- Rabbit
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ARG66958.html
