Crystallography and Cryo-EM - Products and Services

ThermoFluor Screens are used for thermal shift assays, which help determine the stability of proteins under various conditions. By stabilising conditions, researchers can improve the likelihood of obtaining high-quality crystals for X-ray crystallography or stable samples for Cryo-EM. Jena Bioscience provides a variety of ThermoFluor screens tailored to different types of proteins and research needs, simplifying the screening process with pre-formulated buffers and reagents.

Crystallography Screening are pre-formulated kits containing a wide range of conditions to identify suitable crystallisation conditions for proteins. These kits include diverse reagents to test pH, salts, and precipitants, streamlining the process of finding optimal crystallisation conditions.

Crystallography Optimisation can be utilised after initial screening, fine-tuning conditions to grow well-diffracting crystals is crucial. Jena Bioscience offers optimisation kits and reagents that help refine crystallisation conditions by varying component concentrations, adjusting temperatures, or adding additives.

Phasing Solutions are vital for determining the phase of diffracted X-rays is a key step in crystallography. Jena Bioscience provides heavy atom compounds and derivatives, selenomethionine labeling kits, and other tools to aid in experimental phasing techniques like MAD (Multi-wavelength Anomalous Diffraction) and SAD (Single-wavelength Anomalous Diffraction).

Cryo-EM Grids and Reagents a key in Cryo-EM, and Jena Bioscience understand this by offering a range of grids, vitrification tools, and reagents essential for sample preparation and optimisation. Proper screening of these conditions is critical for obtaining high-resolution images, aiding researchers in achieving optimal sample vitrification and imaging.

Cryo-EM Sample Preparation where optimisation in Cryo-EM involves improving the quality of the sample grid, reducing ice thickness, and achieving uniform particle distribution for better results can be the difference in research. Jena Bioscience supplies products to assist with these steps, ensuring high-quality cryo-EM data and trustworthy results.

Cryo-EM Map Interpretation for interpreting electron density maps, fitting atomic models, and validating structures, Jena Bioscience provides software tools and reagents, facilitating the accurate analysis of cryo-EM data.