List Laboratories Inc
List Labs is a leading manufacturing company that has over 45 years of experience in production of bacterial products that include native bacterial toxin, recombinant toxins and Lipopolysaccharides which are relevant for vaccines development, studies in toxin research, drug research and used for infectious disease studies worldwide.
With a rich history marked by innovation, List Labs was one of the first to manufacture live microbiomes for clinical trials, contributing significantly to the field of microbiome therapeutics.
More info on List Laboratories
The company’s state-of-the-art facilities in Campbell, California, along with their team of purification experts enables stringent quality control production of a wide range of native toxins and live biotherapeutic products (LBPs) aimed at rebalancing the human microbiome to address various health conditions.
As List Labs continues to expand their capabilities, they remain committed to supporting clients from concept to commercial production, with plans to enhance its cGMP manufacturing for Phase III and commercial capabilities by 2024.
Key properties that set apart the range of List Lab products are their production from native strains that benefits researchers and its impeccable manufacturing standards that includes:
- Effective maintenance of the structural and immunological integrity
- High Purification capability
- Low endotoxin residual levels
- Lot to Lot consistency through stringent quality assessment
- High characterisations of the strain
Native Toxins from List Labs
- Pertussis Toxin – Used in Vaccine development, EAE models of MS, Signal Transduction studies.
- Cholera Toxin – Used in Vaccine Adjuvants, Vaccine developments, Trace Neuromuscular junctions and Signal Transduction studies.
- Diphtheria Toxin – Used as vaccine carries, vaccine development, Immunological research and Apoptosis studies.
- Tetanus Toxin - As Vaccine carriers and development, trace neuromuscular junctions.
- FRET Peptide Substrates for Botulinum Toxin Type A detection – Used for detection of toxins in Food, clinical, environmental samples, screening and characterisation of Toxin A inhibitors.
List Labs expertise in Bacterial product also lends its services to highly purified GMP Lipopolysaccharides production for clinical trials in R&D labs, including a range of LPS from other micro-organisms that include E. coli, Salmonella Minnesota, Salmonella Typhimurium, Bordetella Pertussis, and Clostridium Difficile.
List Labs, 45 years of expertise have made them one of the most experienced CDMOs for Live Biotherapeutic Products, having worked in numerous microbiome projects using gut, skin and vaginal bacteria for developing a highly scalable cGMP process to produce LBPs for anaerobic and aerobic organisms.
List Labs Product Portfolio |
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