Tumor modelling facilitates the study of tumor growth in the tumor microenvironment. Therapies that affect the tumor microenvironment are critical for advancing the fight against cancer as emerging therapies target the network of signaling pathways essential for tumor growth and metastasis. Patient derived tumor models, including melanoma cell lines and tumor xenografts, are invaluable tools to study normal and malignant cells, tumor formation and drug resistance. 

A diverse panel of melanoma cell lines, now available from Rockland Immunochemicals, is required to account for the varied genetic signatures of tumors, especially if the scientific goal is to establish drug sensitivity for tumor inhibition, therapy resistance, or tumor dormancy. Tumor xenografts are available from Rockland produced on a custom basis in murine models