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Proteins and Peptides

Gamma Synuclein Pre-formed Fibrils (Type 1)

Product Sizes
100 ug
SPR-459-100UG
2 x 100 ug
SPR-459-2X100UG
5 x 100 ug
SPR-459-5X100UG
About this Product
SKU:
SPR-459
Additional Names:
BCSG1 Aggregate Protein, Breast cancer specific gene 1 Aggregate Protein, Breast cancer specific Protein 1 Agreggates, Gamma-synuclein Aggregate Protein, Persyn Aggregate Protein, PRSN Aggregate Protein, SNCG Aggregate Protein, SR Aggregate Protein, Synoretin Aggregate Protein, Synuclein gamma Aggregate Protein, SYUG_HUMAN Aggregate Protein
Application:
Cell-based/Functional Assay, SDS-PAGE, Western Blot
Extra Details:
Gamma synuclein is a neuronal protein found in peripheral and motor nerve systems. It has been implicated in the hippocampal axon pathology in Parkinson's Disease (1). A change in the expression of gamma synuclein has been observed in the retina of patients with Alzheimer's disease (2). Its expression in breast tumors is also a marker for tumor progression (3).
Molecular Weight:
13.33 kDa
Purity:
>95%
Purification:
Ion Exchange
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
StressMarq Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
TEM of Active Human Recombinant Gamma Synuclein Protein Pre-formed Fibrils (Type 1) (SPR-459)
Thioflavin T is a fluorescent dye that binds to beta sheet-rich structures, such as those in gamma synuclein fibrils. Increased fluorescence (correlated to gamma synuclein fibrillization) is seen when human gamma synuclein monomer (SPR-407) is combined with human gamma synuclein PFFs (SPR-459).