ER Stress
Brefeldin A
ER stress inducer. A specific inhibitor of protein translocation from ER to Golgi.
Product Base Number: 10-1071 Size: 5mg Size: 25mg
Thapsigargin
R stress inducer. Potent inhibitor of sarcoplasmic reticulum Ca2+ ATPase.
Product Base Number: 10-2105 Size: 1mg Size: 5mg
Tunicamycin
ER stress inducer. Inhibits GlucNAc phosphostransferase thereby inhibiting glycoprotein biosynthesis.
Product Base Number: 10-2111 Size: 5mg Size: 25mg
4μ8C
R stress inhibitor. IRE1 ribonuclease inhibitor.
Product Base Number: 10-1579 Size: 5mg Size: 25mg
TUDCA
A classic ER stress inhibitor. Reduces ER stress and adipose tissue inflammation in a mouse model of high fat diet-induced obesity.
Product Base Number: 10-2782 Size: 500mg Size: 1g
Salubrinal
ER stress inhibitor acting via eIF2α phosphatase inhibition.
Product Base Number: 10-4517 Size: 5mg Size: 25mg
Toyocamycin
UPR inhibitor. Potently inhibits ER stress-induced XBP1 mRNA splicing. Induces apoptosis in pancreatic cancer cells
Product Base Number: 10-2750 Size: 5mg Size: 25mg
Azoramide
UPR inhibitor. Improves ER protein folding and activates ER chaperone capacity to protect cells against ER stress. Displays potent antidiabetic activity by improving insulin sensitivity.
Product Base Number: 10-4629 Size: 10mg Size: 50mg
Borrelidin
UPR inducer. Threonyl-tRNA synthetase inhibitor. Inhibits angiogenesis