Mitochondrial Research
Mitoquinone
A mitochondria-targeted antioxidant displaying cardio- and neuroprotective effects.
Product Base Number: 10-1363 Size: 5mg Size: 25mg
Mito-TEMPO![Mito-TEMPO](/getmedia/90c71492-82b0-4210-b14b-2b4ecdcd42c5/Mito-TEMPO.jpg)
A mitochondria-targeted antioxidant targeting reactive oxygen species.
Product Base Number: 10-4100 Size: 5mg Size: 25mg
AT-101
A small molecule mimic of the BH3 domain of cellular Bcl-2 inhibitors which interferes with the function of Bcl-2-family anti-apoptotic proteins. Induces apoptosis in drug-resistant multiple myeloma cell lines. Apoptosis is activated by the mitochondrial pathway. Cell permeable.
Product Base Number: 10-1165 Size: 10mg Size: 50mg
Mdivi
Selective inhibitor of Dnm1 GTPase (IC50=1-10 µM). Inhibits mitochondrial outer membrane permeabilization. Inhibits mitochondrial division and apoptosis. Cell permeable.
Product Base Number: 10-1179 Size: 5mg Size: 25mg
FCCP![FCCP](/getmedia/43fb4fdb-1cfe-4728-bcf0-e22ba4ac4e90/FCCP.jpg)
FCCP is a potent and reversible inhibitor of mitochondrial oxidative phosphorylation. It depolarizes mitochondrial membrane potential and induces apoptosis
Product Base Number: 10-1182 Size: 10mg Size: 50mg
Betulinic Acid![Betulinic Acid](/getmedia/7fef1cbc-5359-4fb7-a0da-19ad9a11511f/Betulinic-acid.jpg)
Induces mitochondrial permeability pore opening leading to apoptosis in a variety of cell lines.
Product Base Number: 10-2278 Size: 10mg Size: 100mg
Cyclosporine A
Inhibits mitochondrial permeability pore opening inhibiting apoptosis.
Product Base Number: 10-1119 Size: 100mg Size: 500mg
PK-11195![PK-11195](/getmedia/fa731ee1-61f4-47a2-8407-feb0e672c24b/PK11195-supplier__53263-1552326555-356-300.jpg)
PK-11195 is a selective and potent peripheral benzodiazepine receptor, PBR (or TSPO, translocator protein) antagonist. PK11195 is also able to induce apoptosis in a variety of cell lines
Product Base Number: 10-2221 Size: 5mg Size: 25mg
Obatoclax![Obatoclax](/getmedia/3c868746-deb9-42bb-bcd2-487170b3c301/Obatoclax-supplier_.jpg)
Bcl-2 antagonist that overcomes Bcl-2, Bcl-xL, Bcl-w and Mcl-1-mediated resistance to BAX or BAK.
Product Base Number: 10-2660 Size: 5mg Size: 25mg
M-1![M-1](/getmedia/ce58d9bc-e122-4c51-a509-f7675c9f9038/10-1598M1.jpg)
Enhances mitochondrial fusion without interfering with endoplasmic reticulum and lysosome morphology.
Product Base Number: 10-598 Size: 5mg Size: 25mg
N-Oleoylphenylalanine![N-Oleoylphenylalanine](/getmedia/ec2a41e1-32d4-4c70-898a-69c3d2c84e5e/10-1602Oleylphenylalanine.jpg)
N-Oleoylphenyalanine is an endogenous uncoupler of UCP1-independent respiration.
Product Base Number: 10-1602 Size: 5mg Size: 25mg