Mitochondrial Research
Mitoquinone
A mitochondria-targeted antioxidant displaying cardio- and neuroprotective effects.
Product Base Number: 10-1363 Size: 5mg Size: 25mg
Mito-TEMPO
A mitochondria-targeted antioxidant targeting reactive oxygen species.
Product Base Number: 10-4100 Size: 5mg Size: 25mg
AT-101
A small molecule mimic of the BH3 domain of cellular Bcl-2 inhibitors which interferes with the function of Bcl-2-family anti-apoptotic proteins. Induces apoptosis in drug-resistant multiple myeloma cell lines. Apoptosis is activated by the mitochondrial pathway. Cell permeable.
Product Base Number: 10-1165 Size: 10mg Size: 50mg
Mdivi
Selective inhibitor of Dnm1 GTPase (IC50=1-10 µM). Inhibits mitochondrial outer membrane permeabilization. Inhibits mitochondrial division and apoptosis. Cell permeable.
Product Base Number: 10-1179 Size: 5mg Size: 25mg
FCCP
FCCP is a potent and reversible inhibitor of mitochondrial oxidative phosphorylation. It depolarizes mitochondrial membrane potential and induces apoptosis
Product Base Number: 10-1182 Size: 10mg Size: 50mg
Betulinic Acid
Induces mitochondrial permeability pore opening leading to apoptosis in a variety of cell lines.
Product Base Number: 10-2278 Size: 10mg Size: 100mg
Cyclosporine A
Inhibits mitochondrial permeability pore opening inhibiting apoptosis.
Product Base Number: 10-1119 Size: 100mg Size: 500mg
PK-11195
PK-11195 is a selective and potent peripheral benzodiazepine receptor, PBR (or TSPO, translocator protein) antagonist. PK11195 is also able to induce apoptosis in a variety of cell lines
Product Base Number: 10-2221 Size: 5mg Size: 25mg
Obatoclax
Bcl-2 antagonist that overcomes Bcl-2, Bcl-xL, Bcl-w and Mcl-1-mediated resistance to BAX or BAK.
Product Base Number: 10-2660 Size: 5mg Size: 25mg
M-1
Enhances mitochondrial fusion without interfering with endoplasmic reticulum and lysosome morphology.
Product Base Number: 10-598 Size: 5mg Size: 25mg
N-Oleoylphenylalanine
N-Oleoylphenyalanine is an endogenous uncoupler of UCP1-independent respiration.
Product Base Number: 10-1602 Size: 5mg Size: 25mg